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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b66176b4a3fdd740648063fbc02d873bad24509550824dcb4619a811e69acf90' 
  AND token = '04/53SDzp1P2XBkYYQDnmpKiAQl2XWI0VVqDylkaA8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}