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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f341e2c12acd5d096ee81e292d9a74aac3cdf703eb166963187f1d646fb4ad53' 
  AND token = 'yV9SmHoV71EiDJL7ARWCYXsCzzOPD66CCKTar58sUO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}