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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ea6bc15bce85b06795e0375f6ab4119539774b5d8ce2227e3b7a05195890108' 
  AND token = '9XuwXM/AeHifUkixC8ne1+ybB0fTBBFjfH8+gNuesxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}