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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '290f9c202393a5435c653f64ccdace87a46cd3970e83e334947c14c22bc1cfb4' 
  AND token = 'KMPoMNAMSIjq2nq1m9ENA2XYaIvHOY5481rgXe2zkJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00093

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}