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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de61772d6c3c0dd2614d5c37a89e4ab36f175ae592a7e4d13640da53cb7ebe30' 
  AND token = 'Kt/AdTB0z0Fxbf+6adwNDZMeQIIy0L+WWNYYDiAC3ek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}