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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd49575ad0a5691d5c6869cd93713f1e93983586dfd6a4cc4dc9f61fd4da9c858' 
  AND token = 'dpvZAd6GF8jIiOwqUp0wcj2b5N409hcir1I692/9Mgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}