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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46e2a715821b54f1b37567ab3a25b63e7873805b94c88ec4339981563559af96' 
  AND token = 'DLdCJ++teEz1ZxdTa9FO6xZWOW87426WmMplEcIuJ6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}