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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3963f173fc9c6f73df9ab77844a798a927bf3624f8522079122ea30615ce6826' 
  AND token = 'kkYWE1X/eRVYe/dAdFM2n6RLr4xBKHGvYBsd4910eQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00082

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}