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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45e9cb6702bb02062d4ddf6c5a9cc130380ae305bd193843e13859140c968732' 
  AND token = '5BmTRRCiVtIcwyQ+x4XHR+HSfGNNMD5W1ciRXzREg7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00084

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}