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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd18c21ad3d447817b55855638d7097db59e2ea1d456183dd3aa4840c309525d' 
  AND token = 'Zm1A/MzTvpR3nuAZ+Vgdz5RRIthLSo/UTpEwyLp8WaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}