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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dc9da8aa7d22f9fbab804f57da868baa6eb6c14d6bce5941e278e9d4b065601' 
  AND token = 'UVo6XBUZHfeowzGia9rrufvd7IpKY2gdMmbO608x2zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}