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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01378d9de523206074684cc9a32b8dfda300b19087dddc4d612cb37f60e0fcc4' 
  AND token = 'NTYSJZ8RMx3AoQpGBOCZnvW9ICtUebfuun2sw3oQ1qE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}