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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c856df98aaa98fa67a9cf31a2fa0393a658bff257a26123330c879fd4174c3d0' 
  AND token = 'gH5xixsuicfLp8W6nSv0X3Bhog/k0n5j6eAoy8brBDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}