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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ee26611165c8063aa9e8f0782bbd51adecadb5780583e008235edcdf55e3edb' 
  AND token = 'sC4ei/KwGMspLVDfrVgWy7vY87fz5WKE+S/h4MVFn6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}