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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09ecae4a87548a8b48e96e48c382d6dd25bccb3aa9484e5895e4cde08d9743b2' 
  AND token = 'eC+WJd2GgUM2Yh6jCGL0uhr9k7zYmIdGLJ1qUSQ8Fds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}