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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '527beac2922f504a2d88f3fc15e60c0fd815e9e6a4a1d4ecd24702fb7f77e01c' 
  AND token = 'DAPz3BzcgJvuEidIF7eUy2mYYPqY7bys+K1SYl/nJKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}