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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae147b1713dd0defc5bac50ccedf1d2908d805eedabfb505511618c4e70c92d2' 
  AND token = 'Gf49m3c1T1yRnz9nIJP7CuvzpO96cVVC/VWiypU5iUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}