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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '280ca9c34701e3690876985e454d326bc76f63739bd25e7e7f73dad82c87b0e8' 
  AND token = '2RBsp2wdBajEJg+RyIV9OqMNh/OyyK6d35xBrUz7KEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}