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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '647fe154184c5b07faca3e4ac6bc84e1c5c05d50eb15a535db3c56d9adfa8f3b' 
  AND token = 'ITBob38szE2Qrj+mTMZj2UN4+Y9Ayfl/9+HwXbKCaqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}