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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38d8efc35d93fb71d9d814368f41b8fe33692021ef67aa2256efbcd68d03dc05' 
  AND token = 'mDDnnMp6jpBwA0k81AQtjE/+bj6vsyCbm0LdLWqwUIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}