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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '526ee006aa63a3a383e24688db726b3afc8de0835dea8f8b0b99c159f4d2e06b' 
  AND token = 'FcslxWKK6Xrk+8Q0sNpRW+Pkys20WnaCvIvANz+PN6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}