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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '388ddce5a25b478fd30e67d24d9ee8d480a81721f873e1226b6b4601a1fc0bb5' 
  AND token = 'qYiLT33HRf3SRI4il50fi5PWA45zEv6RBrKm6SiNH+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}