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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b9f95375c693f9d07f26188fbab8a3b758eb6dd4e0d3a718e49eff058dc19aa' 
  AND token = 'UizbeANl9ej3apMjz5PYJeGAesZanWGhohi0c4JkCm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}