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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e604603d0400b3283faaa83471c21891817ce17fa5a26e2a41f4e4bfdef21aa8' 
  AND token = 'zjAC8LsS1x+EYJwhiLr5MuDk6qWIHM2jZOmSQwwtpwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}