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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db5f4f50a6532e9b8cd37fddc999914a24bb7e05e532cfae6c02a13e01ce5587' 
  AND token = 'PaFi6xOLtG29bQm+06OLyaIC5JG6rod0RgSlOP4D92E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}