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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a61569ea6bf136c4804167bafc8e55d261d328c98890dbf8ea3bc0ec770b3678' 
  AND token = 'sI4MQxM8FMlkXGH4VX+d+OL97hZMYQ59/1YihmdopdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}