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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a186849390255e8b721ab6cbcdb8141485449d3a3c209b296c0f601ecfa7051' 
  AND token = '/VAL4CVuvNGP0oGG/6PBo8u81O8QnR1pIRGSR0F5v10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00075

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}