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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7f3cc1ed6c455eadeafbce29a1ba832e20a8b83c7beea2571260c537f460c3a' 
  AND token = 'JJha8nBpapVKJyt6WdYwGAYArRrGg6ZAzTC9xJlLUdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}