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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3218fe2f227c26e39331e310a70b36d2af409360043483fbe3b79edc0d46d52' 
  AND token = 'kUby9MR1g6j6qD5oH12euqfTS3BN47Uz3yauVvSzByI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}