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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e0f8ce6573cc42820b1b15d7b54c2f5023bd24e4473283d9e61b49c09c5a86' 
  AND token = '7ofA/+rQBwo4WikLOjo94bfpfyORmCxmPI2S1IcTth4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}