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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ff4e4405fb9832c46d45c8cf19f4e9fa609cb57935d3a25041f08294d2b3789' 
  AND token = 'dVn9kbB0i2pvLf2PnGYfrRaReLsbIZ6RQRFlbWljBhY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}