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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6152e03f51f449e56641a14b6948f0f2e8ab9261a633e2a94356aeebaed5fdea' 
  AND token = 'AWWA42WjJCLYfkFTtx+dnwkE+BnTnPQsxlxKa4gM0GU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}