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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3994c451adb144448936bf55f47894e13e18ab2ace167189c893a1427dc4fb1e' 
  AND token = 'HsgdlR9QM05F+ZA/REDQ+wzFX4MI4pss7Fq5UHLB6rY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}