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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6681b257f316720016e701ac5aa90b758f62a7ad77cf4b8339868dbf303f593' 
  AND token = '3K+S/s8uQ1oy7kTxfduyc4kfrP3TmZsJwxF7TmB0qKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}