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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '922205de363a5ef6548653f40343ae34254b857215f80b41f04940e5a8611c7d' 
  AND token = 'heGyUZY32Y6XvlIt0pyfuR8jZDGu8U3Cbu7tpk+aba8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}