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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ace0fa27b41a48837802611e1c010755d0fdcb3536536e948418b8685de480a9' 
  AND token = 'W2PC/p/Nvgxich8q+i5F32s1RIjWp9o3A3nWi0RbJuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}