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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25541398d7d7ecb8d470da25f28d285b02d3b2d35d54a143d7fa215bf8711fc8' 
  AND token = 'idcmrTZxK2YiRGY7jOjTIJpxpcNB7iayIHZ8JIdPgBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00077

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}