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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2cb45c160d9ab1036b9ed802424434608a52094d1504f4edc3c6669d3977658' 
  AND token = 'C4LHStXE1/sYYOIPtfLgW6WqZSVTtCUJinlDeWCyp4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}