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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e1a1fd65120545b66ffa00a4139d57754d2d7309720a37ad0fafea5afa26e3f' 
  AND token = '1EyDPgdB+QS97piTIuBZ+2TeB49PX7zKfqhlF/mwHoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}