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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8c44771408aaa2755d6dcb92561bc9cfe6f6b3c122f472fe35db271b8dc7a88' 
  AND token = 'Nnxt0vL79kiUaoQFMXU/sD6OTzVjgq0UHhCMGaPb0fc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}