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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e43637b42bee228b8ec356670a1ca3ee49198cfa0faf93d21c51f174bc9d1c7a' 
  AND token = 'fvM5l7tJ35zi4AfhlW43jXZ8NMMuw9Md/K9z2fTTMs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}