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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35866892d7e35fd43cb8e18a7f1431eb9dee9a54ad98b38543ee6147ba743929' 
  AND token = 'tR8gHMN/hdE76zFAV+siLAB1UxNn0bugoGrnvl2zRH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}