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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cee249b732bfde30e2c4c071a00ddb2966ba0d1e45fd3e8b147174e12491714f' 
  AND token = 'Px/afUPUA9umqBYbDqRi/0YjbAYt3pp5JGFcAd1u27E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}