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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f7a0e9c9e17fa6a72851faf1cb45d1c42637fc148630d4d05f1da08201f86d5' 
  AND token = 'SgCkjY4Ybi3I9G7FoAb4GhJ0/O4Afxw9VQXdLYl8fVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}