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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7f7765b74bf16bd0621d94dd4b39d24c1f95d4bc05d0378c0590a8a32cd7d5d' 
  AND token = 'WIJq+m/QmyMH80aICVAnQGteZEXNn6DsavdjiMpWzI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}