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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '600703d36eaa11fd195d562a1a275b933ae3021b5ff8e3572693be9e8fc0eb7d' 
  AND token = 'VmZbGCJMCj1EXSTJClDlS2IXM9n9u4HLG0eovT3THOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}