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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e491eff7d3698024bf337c35e13be6fb788f2c7224aab7763cb45234c99f1f7' 
  AND token = '4pEuLaAtDfD9gDosXrJVK4r0AEiI2uhdyvfjnQ5eYAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}