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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8e42e5a96f831bba99832f17b8cd55467275553e89c70f857ee9262d2b2947c' 
  AND token = 'gV4XEeGPvpNfao1I2dgIIzgARkM4TrF7+jRcmfqhT2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}