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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9885a62dcad57915b596ce906d3ee551b328c257940dc1507df7ac185d1c7fea' 
  AND token = '+qB5i8t5sVw9VEzWm8R/M5aryfX2pdSFP1pt8rx3h54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}