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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7e3aaf854c1d854a8612e5a21a5096b6065bda288ea85c15feb349d9696c189' 
  AND token = '1kxGV+057a5WQq7WNb09JS3/i3G0tuU8eRgQ1jdoZpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}